Trifluridine
Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase. TFT also inhibits thymidylate synthase (TS), a rate-limiting enzyme of DNA biosynthesis, and is incorporated into DNA.
Product Specifications
CAS Number
70-00-8
Product Name Alternative
NSC 75520 | NSC 529182 | TFT | Trifluridine
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 59 mg/mL (199.18 mM) ; Water: 59 mg/mL (199.18 mM) ; DMSO: 59 mg/mL (199.18 mM)
Smiles
O=C1NC (C (C (F) (F) F) =CN1[C@@H]2O[C@H] (CO) [C@@H] (O) C2) =O
Molecular Formula
C10H11F3N2O5
Molecular Weight
296.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- ((2R,4S,5R) -4-hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) -5- (trifluoromethyl) pyrimidine-2,4 (1H,3H) -dione.
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