BX-912
BX-912 (BX912) is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 26 nM; blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis.
Product Specifications
CAS Number
702674-56-4
Product Name Alternative
BX912 | BX 912
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (N1CCCC1) NC2=CC=CC (NC3=NC=C (Br) C (NCCC4=CNC=N4) =N3) =C2
Molecular Formula
C20H23BrN8O
Molecular Weight
471.3536
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Pyrrolidinecarboxamide, N-[3-[[5-bromo-4-[[2- (1H-imidazol-5-yl) ethyl]amino]-2-pyrimidinyl]amino]phenyl]-
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