Brimonidine Tartrate
Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension. (In Vitro) :[3H]Brimonidine (UK 14304) is a full agonist at alpha 2-adrenergic receptors. [3H]Brimonidine (UK 14304) labels at least 2 specific binding sites in human brain that both have the characteristics of an alpha 2-adrenergic binding site. GTP decreases agonist binding at both of these sites, but with different potencies at each site.
Product Specifications
CAS Number
70359-46-5
Product Name Alternative
AGN 190342LF | Alphagan P
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 75 mg/mL (169.59 mM) ; DMSO: 88 mg/mL (198.99 mM)
Smiles
C1CN=C (N1) NC2=C (C3=NC=CN=C3C=C2) Br.[C@@H] ([C@H] (C (=O) O) O) (C (=O) O) O
Molecular Formula
C15H16BrN5O6
Molecular Weight
442.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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