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Sodium etidronate

A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover. (In Vitro) :Etidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.

Product Specifications

CAS Number

7414-83-7

Product Name Alternative

Etidronic Acid | Didronel | HEDP | Hydroxyethylidene Diphosphonic Acid

Purity

>98% (HPLC)

Solubility

Water: 11.5 mg/mL

Smiles

CC (O) (P (O) (O) =O) P (O) (O) =O

Molecular Formula

C2H6Na2O7P2

Molecular Weight

249.99

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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