Batefenterol

A bifunctional M3 mAChR antagonist and β2-adrenoceptor agonist (MABA) with pKi/pEC50 of 8.7/9.6 for hM3/hβ2 respectively; shows weak effect on β1; the first MABA compound to enter clinical trials and demonstrate proof of concept and efficacy in COPD.COPD Phase 2 Clinical.

Product Specifications

CAS Number

743461-65-6

Product Name Alternative

GSK961081 | TD-5959

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM

Smiles

O=C (OC1CCNCC1) NC2=CC=CC=C2 (CCC (NC3=CC (OC) =C (CNC[C@H] (O) C4=CC=C (O) C5=C4C=CC (N5) =O) C=C3Cl) =O) C6=CC=CC=C6

Molecular Formula

C40H42ClN5O7

Molecular Weight

740.2438

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[ (2R) -2- (1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl) -2-hydroxyethyl]amino]methyl]-5-methoxyphenyl]amino]-3-oxopropyl]-4-piperidinyl ester