Hydroxychloroquine sulfate
Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. (In Vitro) :Hydroxychloroquine sulfate is a synthetic antimalarial drug derived from 4-aminoquinoline; it has been used for several decades for the treatment of some rheumatic diseases such as rheumatoid arthritis (RA) . Five micromolar Hydroxychloroquine sulfate or chloroquine also has no measurable effect on intracellular pH, although these concentrations can inhibit TLR9 or 7 signaling induced by DNA or RNA ligands. (In Vivo) :Hydroxychloroquine sulfate is prescribed for the treatment of lupus, and both Hydroxychloroquine sulfate and its analog chloroquine inhibit TLR7 and 9 signaling.
Product Specifications
CAS Number
747-36-4
Product Name Alternative
HCQ | NSC 4375
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 67 mg/mL (154.39 mM)
Smiles
CCN (CCO) CCCC (NC1=CC=NC2=CC (Cl) =CC=C12) C.O=S (O) (O) =O
Molecular Formula
C18H26ClN3O·H2SO4
Molecular Weight
433.95
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- ((4- ((7-chloroquinolin-4-yl) amino) pentyl) (ethyl) amino) ethan-1-ol sulfate
Available Sizes
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