Cefmenoxime hydrochloride

Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic. (In Vitro) :Cefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL. (In Vivo) :Cefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria.

Product Specifications

CAS Number

75738-58-8

Product Name Alternative

SCE-1365

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO: 8 mg/mL

Smiles

CN1N=NN=C1SCC2=C (N3C (=O) C (C3SC2) NC (=O) /C (=N/OC) /C4=CSC (=N4) N) C (=O) O.CN1N=NN=C1SCC2=C (N3C (=O) C (C3SC2) NC (=O) /C (=N/OC) /C4=CSC (=N4) N) C (=O) O.Cl

Molecular Formula

C32H35ClN18O10S6

Molecular Weight

1059.58

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

7-[[ (2E) -2- (2-amino-1,3-thiazol-4-yl) -2-methoxyiminoacetyl]amino]-3-[ (1-methyltetrazol-5-yl) sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; hydrochloride