Arteether
Arteether, a new antimalarial drug. (In Vitro) :The antimalarial activity of Artemotil is test in vitro against chloroquine-resistant and chloroquine-sensitive Plasmodium falciparum parasites. The mean 50% inhibitory concentration (IC50) for Artemotil is 1.61 nM (range 1.57-1.92 nM) . Artemotil is approximately 2.5-fold more potent than artemisinin. (In Vivo) :Artemotil treatment (25 mg/kg; intravenous injection; daily; for 7 days; Sprague-Dawley male rats) shows anorectic toxicity and causes significant reductions in food consumption and body weight after day 2. AUC on day 7 is 5-fold higher than AUC on day 1. The elimination t1/2 of Artemotil is also prolonged from 13.7 hours (day 1) to 31.2 hours (day 7) .
Product Specifications
CAS Number
75887-54-6
Product Name Alternative
Artemotil | Dihydroartemisinin ethyl ether | NSC 665971
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
C[C@H]1[C@@H] (OCC) O[C@@]2 ([H]) [C@]34[C@@] ([C@H] (C) CC[C@]41[H]) ([H]) CC[C@@] (O2) (C) OO3
Molecular Formula
C17H28O5
Molecular Weight
312.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(3R,5aS,6R,8aS,9R,10S,12R,12aR) -10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano (4,3-j) -1,2-benzodioxepin
Available Sizes
Explore Other Products
Browse additional items from our catalog
MAP2K1 (MAP Kinase Kinase 1, MMAP2K1, MAPKK1, MEK1, MKK1, PRKMK1) (AP)
MAP2K1 (MAP Kinase Kinase 1, MMAP2K1, MAPKK1, MEK1, MKK1, PRKMK1) (AP)