KM11060
A potent corrector of the F508del-CFTR trafficking defect that partially restores F508del trafficking and increases maturation significantly in BHK cells (10 nM for 24 h or 10 uM for 2 h) ; also can significantly increase plasma lipoxin A4 levels in F508del relevant to wildtype mice.
Product Specifications
CAS Number
774549-97-2
Product Name Alternative
KM 11060 | KM-11060
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=S (N1CCN (C2=CC=NC3=CC (Cl) =CC=C23) CC1) (C4=CC=C (Cl) C=C4) =O
Molecular Formula
C19H17Cl2N3O2S
Molecular Weight
422.3282
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Quinoline, 7-chloro-4-[4-[ (4-chlorophenyl) sulfonyl]-1-piperazinyl]-
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