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KM11060

A potent corrector of the F508del-CFTR trafficking defect that partially restores F508del trafficking and increases maturation significantly in BHK cells (10 nM for 24 h or 10 uM for 2 h) ; also can significantly increase plasma lipoxin A4 levels in F508del relevant to wildtype mice.

Product Specifications

CAS Number

774549-97-2

Product Name Alternative

KM 11060 | KM-11060

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=S (N1CCN (C2=CC=NC3=CC (Cl) =CC=C23) CC1) (C4=CC=C (Cl) C=C4) =O

Molecular Formula

C19H17Cl2N3O2S

Molecular Weight

422.3282

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Quinoline, 7-chloro-4-[4-[ (4-chlorophenyl) sulfonyl]-1-piperazinyl]-

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