GNF-2
A potent, allosteric, non-ATP competitive Bcr-Abl inhibitor that shows exclusive antiproliferative activity toward Bcr-abl-transformed cells; causes growth inhibition of Bcr-Abl positive cell lines with IC50s of 273 nM (K562) and 268 nM (SUP-B15) ; inhibits mutant Bcr-Abl E255V, Y253H cell growth.
Product Specifications
CAS Number
778270-11-4
Product Name Alternative
GNF 2 | GNF2
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 45 mg/mL
Smiles
O=C (N) C1=CC=CC (C2=NC=NC (NC3=CC=C (OC (F) (F) F) C=C3) =C2) =C1
Molecular Formula
C18H13F3N4O2
Molecular Weight
374.3166
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, 3-[6-[[4- (trifluoromethoxy) phenyl]amino]-4-pyrimidinyl]-
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