GNF-5
GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22±0.1 uM (Wild type Abl) .
Product Specifications
CAS Number
778277-15-9
Product Name Alternative
GNF-5 | GNF 5 | GNF5.
Purity
>98% (HPLC)
Solubility
Ethanol: 20 mg/mL warmed (47.8 mM) ; DMSO: 83 mg/mL (198.38 mM)
Smiles
O=C (NCCO) C1=CC=CC (C2=NC=NC (NC3=CC=C (OC (F) (F) F) C=C3) =C2) =C1
Molecular Formula
C20H17F3N4O3
Molecular Weight
418.37
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2-Hydroxyethyl) -3-[6-[[4- (trifluoromethoxy) phenyl]amino]-4-pyrimidinyl]benzamide
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