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Apoptosis Activator 2

An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation; leads to the destruction of cells (Apaf-1 dependent) with IC50 of 4 uM; exert cytostatic and cytotoxic effects on a variety of cancer cell lines while having little or no activity against the normal cell lines tested.

Product Specifications

CAS Number

79183-19-0

Field of Research

Cell Biology

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 46 mg/mL

Smiles

O=C1N (CC2=CC=C (Cl) C (Cl) =C2) C3=C (C=CC=C3) C1=O

Molecular Formula

C15H9Cl2NO2

Molecular Weight

306.1435

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1H-Indole-2,3-dione, 1-[ (3,4-dichlorophenyl) methyl]-

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