Apoptosis Activator 2
An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation; leads to the destruction of cells (Apaf-1 dependent) with IC50 of 4 uM; exert cytostatic and cytotoxic effects on a variety of cancer cell lines while having little or no activity against the normal cell lines tested.
Product Specifications
CAS Number
79183-19-0
Field of Research
Cell Biology
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 46 mg/mL
Smiles
O=C1N (CC2=CC=C (Cl) C (Cl) =C2) C3=C (C=CC=C3) C1=O
Molecular Formula
C15H9Cl2NO2
Molecular Weight
306.1435
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Indole-2,3-dione, 1-[ (3,4-dichlorophenyl) methyl]-
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