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Nodinitib-1

A potent and selective NOD1 inhibitor with IC50 of 0.56 uM; no inhibition on NOD1, TNFα (IC50> 20 uM) and dIKKγ/NEMO, MYD88, FLIP, CARD6, APAF1 or NLRC4; inhibits IL-8 production induced by NOD1 ligand and γ-tri-DAP-induced expression of the prototypical NF-κB target gene IκBα at the mRNA level.

Product Specifications

CAS Number

799264-47-4

Product Name Alternative

ML-130 | CID-1088438 | Nodinitib

Purity

>98% (HPLC)

Solubility

DMSO: 20 mg/mL

Smiles

NC1=NC2=CC=CC=C2N1S (=O) (C3=CC=C (C) C=C3) =OInChI=1S/C14H13N3O2S/c1-10-6-8-11 (9-7-10) 20 (18,19) 17-13-5-3-2-4-12 (13) 16-14 (17) 15/h2-9H,1H3, (H2,15,16)

Molecular Formula

C14H13N3O2S

Molecular Weight

287.3369

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1H-Benzimidazol-2-amine, 1-[ (4-methylphenyl) sulfonyl]-

Available Sizes

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