Nodinitib-1
A potent and selective NOD1 inhibitor with IC50 of 0.56 uM; no inhibition on NOD1, TNFα (IC50> 20 uM) and dIKKγ/NEMO, MYD88, FLIP, CARD6, APAF1 or NLRC4; inhibits IL-8 production induced by NOD1 ligand and γ-tri-DAP-induced expression of the prototypical NF-κB target gene IκBα at the mRNA level.
Product Specifications
CAS Number
799264-47-4
Product Name Alternative
ML-130 | CID-1088438 | Nodinitib
Purity
>98% (HPLC)
Solubility
DMSO: 20 mg/mL
Smiles
NC1=NC2=CC=CC=C2N1S (=O) (C3=CC=C (C) C=C3) =OInChI=1S/C14H13N3O2S/c1-10-6-8-11 (9-7-10) 20 (18,19) 17-13-5-3-2-4-12 (13) 16-14 (17) 15/h2-9H,1H3, (H2,15,16)
Molecular Formula
C14H13N3O2S
Molecular Weight
287.3369
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Benzimidazol-2-amine, 1-[ (4-methylphenyl) sulfonyl]-
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