Fluticasone propionate
Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis. (In Vitro) :Fluticasone propionate inhibits TNFα-induced E-selectin expression, with an IC50 of 1 nM.
Product Specifications
CAS Number
80474-14-2
Product Name Alternative
Fluticasone 17-Propionate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 5 mg/mL (9.98 mM) ; DMSO: 100 mg/mL (199.77 mM)
Smiles
CCC (O[C@]1 (C (SCF) =O) [C@H] (C) C[C@@H]2[C@]1 (C) C[C@H] (O) [C@@]3 (F) [C@H]2C[C@H] (F) C4=CC (C=C[C@@]43C) =O) =O
Molecular Formula
C25H31F3O5S
Molecular Weight
500.57
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(6S,8S,9R,10S,11S,13S,14S,16R,17R) -6,9-difluoro-17- (((fluoromethyl) thio) carbonyl) -11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
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