PHTPP
A potent, selective antagonist of estrogen ERβ receptor; exhibits 36-fold selective for ERβ, and is fully effective as an ERα antagonist, while exhibiting no significant agonism on ERβ or Erα; enhances SKOV3 and OV2008 ovarian cancer cell growth in in vitro assays.
Product Specifications
CAS Number
805239-56-9
Product Name Alternative
PHTPP
Purity
>98% (HPLC)
Solubility
DMSO: 14 mg/mL (33 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
OC1=CC=C (C2=C3N=C (C (F) (F) F) C=C (C (F) (F) F) N3N=C2C4=CC=CC=C4) C=C1
Molecular Formula
C20H11F6N3O
Molecular Weight
423.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-[2-Phenyl-5,7-bis (trifluoromethyl) pyrazolo[1,5-a]pyrimidin-3-yl]phenol
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