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GSK-180736A

A highly selective and potent GRK2 inhibitor with IC50 of 0.77 uM; displays >400-fold selective for GRK2 over both GRK1 and GRK5, with no inhibition on PKA; also inhibits ROCK with IC50 of 0.1 uM.

Product Specifications

CAS Number

817194-38-0

Product Name Alternative

GSK 180736A | GSK180736A

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 30 mg/mL

Smiles

CC1=C (C (NC (=O) N1) C2=CC=C (C=C2) F) C (=O) NC3=CC4=C (C=C3) NN=C4

Molecular Formula

C19H16FN5O2

Molecular Weight

365.3611

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5-Pyrimidinecarboxamide, 4- (4-fluorophenyl) -1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-

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