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Palbociclib (PD0332991) Isethionate

Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.

Product Specifications

CAS Number

827022-33-3

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Water: 50 mg/mL warmed (87.15 mM)

Smiles

OCCS (O) (=O) =O.CC (=O) C1=C (C) C2=CN=C (NC3=NC=C (C=C3) N3CCNCC3) N=C2N (C2CCCC2) C1=O

Molecular Formula

C24H29N7O2·C2H6O4S

Molecular Weight

573.66

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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