Palbociclib (PD0332991) Isethionate
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
Product Specifications
CAS Number
827022-33-3
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 50 mg/mL warmed (87.15 mM)
Smiles
OCCS (O) (=O) =O.CC (=O) C1=C (C) C2=CN=C (NC3=NC=C (C=C3) N3CCNCC3) N=C2N (C2CCCC2) C1=O
Molecular Formula
C24H29N7O2·C2H6O4S
Molecular Weight
573.66
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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