Nefazodone hydrochloride
Nefazodone hydrochloride is an antidepressant drug. (In Vitro) :Nefazodone hydrochloride (BMY-13754) is a phenylpiperazine antidepressant with a mechanism of action that is distinct from those of other currently available drugs. Nefazodone hydrochloride potently and selectively blocks postsynaptic serotonin (5-hydroxytryptamine; 5-HT) 5-HT2A receptors and moderately inhibits serotonin and noradrenaline (norepinephrine) reuptake. Nefazodone hydrochloride is also an inhibitor of the hepatic P-450 isoenzyme CYP3A4.
Product Specifications
CAS Number
82752-99-6
Product Name Alternative
BMY 13754 | MJ13754-1
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: ~11 mg/mL at 60 °C
Smiles
O=C1N (CCCN2CCN (C3=CC=CC (Cl) =C3) CC2) N=C (CC) N1CCOC4=CC=CC=C4.[H]Cl
Molecular Formula
C25H33Cl2N5O2
Molecular Weight
506.47
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (3- (4- (3-chlorophenyl) piperazin-1-yl) propyl) -5-ethyl-4- (2-phenoxyethyl) -2,4-dihydro-3H-1,2,4-triazol-3-one hydrochloride
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