R406 free base
R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 1.
Product Specifications
CAS Number
841290-80-0
Purity
>98% (HPLC)
Solubility
DMSO: 21 mg/mL (44.63 mM)
Smiles
COC1=CC (NC2=NC=C (F) C (NC3=NC4=C (OC (C) (C) C (=O) N4) C=C3) =N2) =CC (OC) =C1OC
Molecular Formula
C22H23FN6O5
Molecular Weight
470.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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