Enalaprilat Dihydrate
Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM. (In Vitro) :Enalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM. (In Vivo) :Enalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP) -lowering effect in rabbits.
Product Specifications
CAS Number
84680-54-6
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:70 mg/mL (200.91 mM) ; Ethanol:<1 mg/mL (<1 mM) ; Water:<1 mg/mL (<1 mM)
Smiles
O.O.C[C@H] (N[C@@H] (CCC1=CC=CC=C1) C (O) =O) C (=O) N1CCC[C@H]1C (O) =O |r, c:8,10, t:6|
Molecular Formula
C18H24N2O5.2H2O
Molecular Weight
348.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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