NVP-BEP800
A potent and selective Hsp90β inhibitor with IC50 of 58 nM; shows >70-fold selective against Grp94 and Trap-1; induces ErbB2, B-Raf (V600E), Raf-1, Akt and Hsp70 induction in A375 melanoma and BT-474 breast cancer cell lines; orally bioactive.Breast Cancer Preclinical.
Product Specifications
CAS Number
847559-80-2
Product Name Alternative
VER-82576 | VER82576
Purity
>98% (HPLC)
Solubility
DMSO: 6.2 mg/mL (Need ultrasonic)
Smiles
O=C (C1=CC2=C (C3=CC (OCCN4CCCC4) =C (Cl) C=C3Cl) N=C (N) N=C2S1) NCC
Molecular Formula
C21H23Cl2N5O2S
Molecular Weight
480.4106
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Thieno[2,3-d]pyrimidine-6-carboxamide, 2-amino-4-[2,4-dichloro-5-[2- (1-pyrrolidinyl) ethoxy]phenyl]-N-ethyl-
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