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NVP-BEP800

A potent and selective Hsp90β inhibitor with IC50 of 58 nM; shows >70-fold selective against Grp94 and Trap-1; induces ErbB2, B-Raf (V600E), Raf-1, Akt and Hsp70 induction in A375 melanoma and BT-474 breast cancer cell lines; orally bioactive.Breast Cancer Preclinical.

Product Specifications

CAS Number

847559-80-2

Product Name Alternative

VER-82576 | VER82576

Purity

>98% (HPLC)

Solubility

DMSO: 6.2 mg/mL (Need ultrasonic)

Smiles

O=C (C1=CC2=C (C3=CC (OCCN4CCCC4) =C (Cl) C=C3Cl) N=C (N) N=C2S1) NCC

Molecular Formula

C21H23Cl2N5O2S

Molecular Weight

480.4106

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Thieno[2,3-d]pyrimidine-6-carboxamide, 2-amino-4-[2,4-dichloro-5-[2- (1-pyrrolidinyl) ethoxy]phenyl]-N-ethyl-

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