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MC-1568

A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.

Product Specifications

CAS Number

852475-26-4

Product Name Alternative

MC1568

Purity

>98% (HPLC)

Solubility

DMSO: 18.5 mg/mL

Smiles

O=C (NO) /C=C/C1=CC=C (/C=C/C (C2=CC=CC (F) =C2) =O) N1C

Molecular Formula

C17H15FN2O3

Molecular Weight

314.311

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Propenamide, 3-[5-[ (1E) -3- (3-fluorophenyl) -3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E) -

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