WP1066
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. Phase 1.
Product Specifications
CAS Number
857064-38-1
Product Name Alternative
STAT Inhibitor III
Purity
>98% (HPLC)
Solubility
DMSO: 71 mg/mL (199.31 mM)
Smiles
O=C (N[C@H] (C1=CC=CC=C1) C) /C (C#N) =C/C2=NC (Br) =CC=C2
Molecular Formula
C17H14BrN3O
Molecular Weight
356.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S, E) -3- (6-bromopyridin-2-yl) -2-cyano-N- (1-phenylethyl) acrylamide
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