IOX1
IOX1 is a potent, broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases, with IC50 of <1 uM gainst the KDM3, KDM4 and KDM6, 5-25 uM against the KDM5 and KDM2/7; IOX1 is less potent against BBOX1 (IC50=196 uM) ; chelates to Fe (II) in the active site of 2OG oxygenases; suppresses the proliferation and migration of vascular smooth muscle cells induced by angiotensin II.
Product Specifications
CAS Number
5852-78-8
Product Name Alternative
IOX 1 | IOX-1
Purity
>98% (HPLC)
Solubility
DMSO: 24 mg/mL
Smiles
O=C (C1=C2C=CC=NC2=C (O) C=C1) O
Molecular Formula
C10H7NO3
Molecular Weight
189.1675
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5-Quinolinecarboxylic acid, 8-hydroxy-
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
