Inosine
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (In Vitro) :Inosine dose-dependently stimulates cAMP production mediated through the A2AR.Inosine dose-dependently induces hA2AR-mediated ERK1/2 phosphorylation.Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes.
Product Specifications
CAS Number
58-63-9
Product Name Alternative
Inosine | NSC 20262 | NSC-20262 | NSC20262
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 47 mg/mL warmed (175.22 mM) ; DMSO: 53 mg/mL warmed (197.59 mM)
Smiles
OC[C@@H]1[C@H] ([C@H] ([C@H] (N2C=NC3=C (N=CN=C32) O) O1) O) O
Molecular Formula
C10H12N4O5
Molecular Weight
268.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Inosine
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