TWS119
A GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; can induce neurogenesis in murine ESCs; reduces Cdon levels and aberrant Cx43 activitiesin rat cardiomyocytes; attenuates rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats.
Product Specifications
CAS Number
601514-19-6
Product Name Alternative
TWS 119 | TWS-119
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C1=CC (=CC (=C1) N) C2=CC3=C (N2) N=CN=C3OC4=CC=CC (=C4) O
Molecular Formula
C18H14N4O2
Molecular Weight
318.3293
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Phenol, 3-[[6- (3-aminophenyl) -7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-
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