Odanacatib
A potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 0.2 nM; displays >300-fold selectivity over cathepsin B, L, S, F, and V; demonstrates the potentiation for the treatment of osteoporosis and other skeletal disorders associated with excessive bone remodeling.Osteoporosis Phase 3 Clinical.
Product Specifications
CAS Number
603139-19-1
Product Name Alternative
MK-0822 | MK 0822 | MK0822
Purity
>98% (HPLC)
Solubility
DMSO: ≥25 mg/mL
Smiles
CC (C) (F) C[C@H] (N[C@@H] (C1=CC=C (C2=CC=C (S (=O) (C) =O) C=C2) C=C1) C (F) (F) F) C (NC3 (C#N) CC3) =O
Molecular Formula
C25H27F4N3O3S
Molecular Weight
525.5588
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Pentanamide, N- (1-cyanocyclopropyl) -4-fluoro-4-methyl-2-[[ (1S) -2,2,2-trifluoro-1-[4'- (methylsulfonyl) [1,1'-biphenyl]-4-yl]ethyl]amino]-, (2S) -
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