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Amrinone

A positive inotropic cardiotonic (cardiotonic agents) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell. (In Vitro) :Amrinone (Inamrinone) produced a dose-dependent inhibition of ADP-induced rat platelet aggregation in vitro as well as ex vivo in rats. The proliferation of human aortic smooth muscle cells in culture stimulated with FBS or PDGF was also inhibited by amrinone. (In Vivo) :Amrinone (Inamrinone) is administered subcutaneously to rats at a dose of 10 mg/kg/day for 14 days, significant reduction of neointimal thickness was noted.

Product Specifications

CAS Number

60719-84-8

Product Name Alternative

WIN 40,680

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM

Smiles

C1=CN=CC=C1C2=CNC (=O) C (=C2) N

Molecular Formula

C10H9N3O

Molecular Weight

187.2

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

3-amino-5-pyridin-4-yl-1H-pyridin-2-one

Available Sizes

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