Amrinone
A positive inotropic cardiotonic (cardiotonic agents) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell. (In Vitro) :Amrinone (Inamrinone) produced a dose-dependent inhibition of ADP-induced rat platelet aggregation in vitro as well as ex vivo in rats. The proliferation of human aortic smooth muscle cells in culture stimulated with FBS or PDGF was also inhibited by amrinone. (In Vivo) :Amrinone (Inamrinone) is administered subcutaneously to rats at a dose of 10 mg/kg/day for 14 days, significant reduction of neointimal thickness was noted.
Product Specifications
CAS Number
60719-84-8
Product Name Alternative
WIN 40,680
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
C1=CN=CC=C1C2=CNC (=O) C (=C2) N
Molecular Formula
C10H9N3O
Molecular Weight
187.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-amino-5-pyridin-4-yl-1H-pyridin-2-one
Available Sizes
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