AFN-1252
A potent inhibitor of bacterial enoyl-ACP reductase FabI; demonstrates MICs of 0.015 and 0.008 ug/ml for S. aureus ATCC 29213 and S. aureus ATCC 33592 (MRSA), respectively; demonstrates a Staphylococcus-specific spectrum of activity.Bacterial Infection Phase 2 Clinical.
Product Specifications
CAS Number
620175-39-5
Product Name Alternative
API-1252 | Debio-1452
Purity
>98% (HPLC)
Solubility
DMSO: 5.8 mg/mL (Need ultrasonic)
Smiles
O=C (N (C) CC1=C (C) C2=CC=CC=C2O1) /C=C/C3=CC (CC4) =C (N=C3) NC4=O
Molecular Formula
C22H21N3O3
Molecular Weight
375.4204
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propenamide, N-methyl-N-[ (3-methyl-2-benzofuranyl) methyl]-3- (5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-3-yl) -, (2E) -
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