Oltipraz
Oltipraz (RP 35972, NSC 347901) is a cancer chemopreventive agent with inhibitory effect on angiogenesis and tumor growth, inhibits insulin- or hypoxia-induced HIF-1α expression through an increase in ubiquitination; abrogates insulin-induced H (2) O (2) production, thereby preventing H (2) O (2) -enhanced HIF-1alpha expression and promoting its ubiquitination and degradation; inhibits HIF-1α activity and HIF-1α-dependent tumor growth both in vitro and in vivo.Steatohepatitis Phase 3 Clinical.
Product Specifications
CAS Number
64224-21-1
Product Name Alternative
RP 35972 | NSC 347901
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
S=C1SSC (C2=NC=CN=C2) =C1C
Molecular Formula
C8H6N2S3
Molecular Weight
226.3416
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3H-1,2-Dithiole-3-thione, 4-methyl-5- (2-pyrazinyl) -
Available Sizes
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