BGP-15
A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro; has no effect on HSP90 levels, markedly increases the phosphorylation of HSF1 and expression of HSF1 and HSP72 in adipocytes and muscle cells; protects against obesity-induced insulin resistance and orally active; alleviates ventilation-induced diaphragm dysfunction associated with HSP72 induction and PARP-1 inhibition.Diabetes Phase 2 Clinical.
Product Specifications
CAS Number
66611-37-8
Product Name Alternative
BGP 15 | BGP15
Purity
>98% (HPLC)
Solubility
DMSO: 11.33 mg/mL
Smiles
C1CCN (CC1) CC (CON=C (C2=CN=CC=C2) N) O.Cl.Cl
Molecular Formula
C14H24Cl2N4O2
Molecular Weight
351.272
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Pyridinecarboximidamide, N-[2-hydroxy-3- (1-piperidinyl) propoxy]-, hydrochloride (1:2)
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