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Drospirenone

Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. It was shown in animal studies that drospirenone exhibits antiandrogenic activity judging from accessory sex gland growth in castrated, androgen-treated, juvenile rats.

Product Specifications

CAS Number

67392-87-4

Product Name Alternative

1,2-dihydro Spirorenone | ZK 30595

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: 11 mg/mL (30.01 mM) ; DMSO: 73 mg/mL (199.18 mM)

Smiles

O=C1CC[C@]2 (C) [C@@]3 ([H]) CC[C@@] ([C@] (OC4=O) (CC4) [C@]5 ([H]) [C@@]6 ([H]) C5) (C) [C@]6 ([H]) [C@]3 ([H]) C7C (C7) C2=C1

Molecular Formula

C24H30O3

Molecular Weight

366.49

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(2'S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR) -4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,8d,9,9a-tetradecahydro-3'H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthrene-7,2'-furan]-2,5' (3H,4'H) -dione

Available Sizes

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