Drospirenone
Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. It was shown in animal studies that drospirenone exhibits antiandrogenic activity judging from accessory sex gland growth in castrated, androgen-treated, juvenile rats.
Product Specifications
CAS Number
67392-87-4
Product Name Alternative
1,2-dihydro Spirorenone | ZK 30595
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 11 mg/mL (30.01 mM) ; DMSO: 73 mg/mL (199.18 mM)
Smiles
O=C1CC[C@]2 (C) [C@@]3 ([H]) CC[C@@] ([C@] (OC4=O) (CC4) [C@]5 ([H]) [C@@]6 ([H]) C5) (C) [C@]6 ([H]) [C@]3 ([H]) C7C (C7) C2=C1
Molecular Formula
C24H30O3
Molecular Weight
366.49
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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WDFY1 (Protein Wdfy1 Ensembl ENSMUSP00000109138 Ensembl ENSMUSP00000109139 Ensembl ENSMUSP00000040224, WD Repeat and FYVE Domain Containing 1)
