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Nutlin-3b

A p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+) -enantiomer of Nutlin-3 as in comparison with opposite (-) -enantiomer Nutlin-3a.

Product Specifications

CAS Number

675576-97-3

Product Name Alternative

Nutlin 3b

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C ([C@H]2[C@@H] (C3=CC=C (Cl) C=C3) N=C (C4=CC=C (OC) C=C4OC (C) C) N2C (N5CCN ([H]) C (C5) =O) =O) C=C1

Molecular Formula

C30H30Cl2N4O4

Molecular Weight

581.4896

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Piperazinone, 4-[[ (4R,5S) -4,5-bis (4-chlorophenyl) -4,5-dihydro-2-[4-methoxy-2- (1-methylethoxy) phenyl]-1H-imidazol-1-yl]carbonyl]-

Available Sizes

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