1-Azakenpaullone
1-Azakenpaullone is an analog of kenpaullone and is a potent, selective GSK3β inhibitor with IC50 of 18 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=2.0 and 4.2 uM) ; stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells.
Product Specifications
CAS Number
676596-65-9
Product Name Alternative
1-Azakenpaullone
Purity
>98% (HPLC)
Solubility
DMSO: 61 mg/mL (185.9 mM) ; Ethanol: <1 mg/mL; Water: <1 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NC1=CC=CN=C12) CC3=C2NC4=C3C=C (Br) C=C4
Molecular Formula
C15H10BrN3O
Molecular Weight
328.169
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9-bromo-7,12-dihydro-pyrido[3',2':2,3]azepino[4,5-b]indol-6 (5H) -one
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