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1-Azakenpaullone

1-Azakenpaullone is an analog of kenpaullone and is a potent, selective GSK3β inhibitor with IC50 of 18 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=2.0 and 4.2 uM) ; stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells.

Product Specifications

CAS Number

676596-65-9

Product Name Alternative

1-Azakenpaullone

Purity

>98% (HPLC)

Solubility

DMSO: 61 mg/mL (185.9 mM) ; Ethanol: <1 mg/mL; Water: <1 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

O=C (NC1=CC=CN=C12) CC3=C2NC4=C3C=C (Br) C=C4

Molecular Formula

C15H10BrN3O

Molecular Weight

328.169

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

9-bromo-7,12-dihydro-pyrido[3',2':2,3]azepino[4,5-b]indol-6 (5H) -one

Available Sizes

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