PIK-90
PIK-90 is a potent DNA-PK and PI3K inhibitor that inhibits p110α, p110γ and DNA-PK with IC50s of 11, 18 and 13 nM, respectively; inhibits phosphorylation of Akt and S6, blocks the antiapoptotic protein Survivin and driving cell death in malignant glioma the clinical CDK1/2 inhibitor cooperated with roscovitine.
Product Specifications
CAS Number
677338-12-4
Product Name Alternative
PIK90 | PIK 90
Purity
>98% (HPLC)
Solubility
DMSO: < 1 mg/mL
Smiles
O=C (NC1=NC2=C (C=CC (OC) =C2OC) C3=NCCN13) C4=CN=CC=C4
Molecular Formula
C18H17N5O3
Molecular Weight
351.3593
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Pyridinecarboxamide, N- (2,3-dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl) -
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