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Cyanocobalamin

Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. (In Vitro) :Vitamin B12 is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis (especially odd chain fatty acids) and energy production. However, many (though not all) of the effects of functions of B12 can be replaced by sufficient quantities of folic acid (vitamin B9), since B12 is used to regenerate folate in the body. Most vitamin B12 deficiency symptoms are actually folate deficiency symptoms, since they include all the effects of pernicious anemia and megaloblastosis, which are due to poor synthesis of DNA when the body does not have a proper supply of folic acid for the production of thymine due to methyl trapping. When sufficient folic acid is available, all known B12 related deficiency syndromes normalize, save those narrowly connected with the vitamin B12-dependent enzymes Methylmalonyl Coenzyme A mutase, and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase; and the buildup of their respective substrates (methylmalonic acid, MMA) and homocysteine.Coenzyme B12's reactive C-Co bond participates in three main types of enzyme-catalyzed reactions.

Product Specifications

CAS Number

68-19-9

Product Name Alternative

Cobalamin | NSC 80365

Purity

>98% (HPLC)

Solubility

Ethanol: 10 mg/mL (7.37 mM) ; Water: 6 mg/mL (4.42 mM) ; DMSO: 75 mg/mL (55.33 mM)

Smiles

Cc (c (C) c1) cc2c1[n+]3cn2C4C (C (C (O4) CO) OP (OC (CNC (CCC5 (C (C6C7 (C (CC (N) =O) (C (C8=N7[Co+3]39%10 ([N-]6C5=C (C%11=N9C (C (C) (C%11CCC (N) =O) C) =CC%12=N%10C (C (CC (N) =O) (C%12CCC (N) =O) C) =C8C) C) [CH-]#N) CCC (N) =O) C) C) CC (N) =O) C) =O) C) ([O-]) =O) O

Molecular Formula

C63H88CoN14O14P

Molecular Weight

1355.37

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Cobinamide, cyanide phosphate 3'-ester with 5,6-dimethyl-1-alpha-D- ribofuranosylbenzimidazole, inner salt

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