IWP-2
IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses.
Product Specifications
CAS Number
686770-61-6
Product Name Alternative
Inhibitor of Wnt Production-2
Purity
>98% (HPLC)
Solubility
DMF: 22 mg/mL warming (47.14 mM) ; DMSO: 4 mg/mL warming (8.57 mM)
Smiles
O=C (NC1=NC2=CC=C (C) C=C2S1) CSC3=NC (CCS4) =C4C (N3C5=CC=CC=C5) =O
Molecular Formula
C22H18N4O2S3
Molecular Weight
466.6
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N - (6-Methyl-2-benzothiazolyl) -2-[ (3?,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2- d ]pyrim?idin-2-yl) thio]-acetamide
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