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IWP-2

IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses.

Product Specifications

CAS Number

686770-61-6

Product Name Alternative

Inhibitor of Wnt Production-2

Purity

>98% (HPLC)

Solubility

DMF: 22 mg/mL warming (47.14 mM) ; DMSO: 4 mg/mL warming (8.57 mM)

Smiles

O=C (NC1=NC2=CC=C (C) C=C2S1) CSC3=NC (CCS4) =C4C (N3C5=CC=CC=C5) =O

Molecular Formula

C22H18N4O2S3

Molecular Weight

466.6

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N - (6-Methyl-2-benzothiazolyl) -2-[ (3?,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2- d ]pyrim?idin-2-yl) thio]-acetamide

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