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Dimethylenastron

A small molecule inhibitor of the mitotic kinesin Eg5; inhibits endothelial cell proliferation and migration in vitro; exhibits a shorter mitotic arrest, bipolar or multipolar karyokinesis, followed by apoptosis of the daughter cells in dimethylenastron-treated tetraploid cells.

Product Specifications

CAS Number

863774-58-7

Product Name Alternative

Dimethylenastron

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 31 mg/mL

Smiles

O=C1C2=C (NC (NC2C3=CC=CC (O) =C3) =S) CC (C) (C) C1

Molecular Formula

C16H18N2O2S

Molecular Weight

302.3913

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5 (1H) -Quinazolinone, 2,3,4,6,7,8-hexahydro-4- (3-hydroxyphenyl) -7,7-dimethyl-2-thioxo-

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