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INF39

INF39 (NLRP3 inhibitor INF39) is a nontoxic, irreversible, orally available NLRP3 inhibitor that inhibits NLRP3 ATPase and decreases interleukin-1β release from macrophages; significantly inhibit ATP- and nigericin-induced IL-1β release in mouse bone marrow derived macrophages (BMDM) at 10 uM, reduces colonic myeloperoxidase, IL-1β, and TNF Levels in DNBS-treated rats.

Product Specifications

CAS Number

866028-26-4

Product Name Alternative

NLRP3 inhibitor INF39

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

ClC1=C (CC (C (OCC) =O) =C) C=CC=C1

Molecular Formula

C12H13ClO2

Molecular Weight

224.684

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Ethyl 2- (2-chlorobenzyl) acrylate

Available Sizes

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