Tozadenant
A potent, selective adenosine 2A receptor (A2A/NR2B) antagonist with Ki of 11.5 nM.Parkinson's Disease Phase 3 Discontinued (In Vivo) :18F-MNI-444 regional uptake is consistent with A2A receptor distribution in the brain. Selectivity is demonstrated by dose-dependent blocking by tozadenant (1.5, 10.5 mg/kg) and preladenant.
Product Specifications
CAS Number
870070-55-6
Product Name Alternative
SYN-115 | SYN115 | SYN 115
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (N1CCC (C) (O) CC1) NC2=NC3=C (OC) C=CC (N4CCOCC4) =C3S2
Molecular Formula
C19H26N4O4S
Molecular Weight
406.4991
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Piperidinecarboxamide, 4-hydroxy-N-[4-methoxy-7- (4-morpholinyl) -2-benzothiazolyl]-4-methyl-
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