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S1RA

A potent and selective sigma-1 receptor antagonist with Ki of 17 nM; shows excellent selectivity over sigma-2 receptor (Ki>1 uM) ; shows high activity in the mouse capsaicin model of neurogenic pain, exerts dose-dependent antinociceptive effects in several neuropathic pain models.Pain Phase 2 Clinical.

Product Specifications

CAS Number

878141-96-9

Product Name Alternative

E-52862

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

CC1=CC (OCCN2CCOCC2) =NN1C1=CC2=CC=CC=C2C=C1

Molecular Formula

C20H23N3O2

Molecular Weight

337.4155

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Morpholine, 4-[2-[[5-methyl-1- (2-naphthalenyl) -1H-pyrazol-3-yl]oxy]ethyl]-

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